Our Alliance
Mission of the ILD Community Network
To unite, empower, and support individuals and organizations in advancing awareness, research, and care for those impacted by Interstitial Lung Disease.
Connect to ILD experts in your region
Partner with trusted ILD experts in your region to unlock your potential and achieve your goals.
ILD EXPERTS
Naomi Amudala
CRNP, MSN
Naomi Amudala, CRNP, MSN, is a highly experienced nurse practitioner specializing in rheumatology at Penn Medicine in Philadelphia, Pennsylvania. After graduating from MGH Institute of Health Professions in 2009 with a Master’s in Nursing, Naomi joined the division of Rheumatology at Boston University. Her primary focus was evaluating and managing patients with vasculitis as well as acting as co-investigator in multiple clinical trials in vasculitis. In 2018 she moved to Philadelphia and started working at Penn Medicine Rheumatology. The majority of her time continues to be dedicated to the clinical care of patients with vasculitis and other rare diseases as well as engaging in research. In 2022 Naomi joined the board of directors for RhAPP, which is a national organization for APPs and pharmacists in Rheumatology.
Christine Anderson
NP-C
Christine Anderson, NP-C, is a nurse practitioner specializing in pulmonology at Duke Health in Durham, North Carolina. She is originally from Canada and graduated from The University of Western Ontario with a Bachelors in Science in Nursing in London, Ontario back in 1999. After graduation, she moved to Durham, NC to start a nursing career at Duke University Health System. The majority of her nursing career has been in cardiology from Cardiac Step-Down to Cardiac Intensive Care Unit to the Cardiac Cath Lab. In 2005, Christine obtained a Masters in Science in Nursing with a Leadership focus and became the nurse manager of the Electrophysiology Lab at Duke Hospital. After downsizing the department, she moved over to the Duke Clinical Research Institute as a nurse clinician working on cardiology clinical trials. She truly missed patient care and went back to school and graduated with a post-master’s certificate as an Adult-Gerontologic Nurse Practitioner in 2015. Christine worked at Duke Cardiology of Lumberton for one year before coming back to main campus of Duke University Hospital and starting a new career in pulmonary medicine. Now she is the nurse practitioner for the Duke Interstitial Lung Disease Clinic where she still practices. For her last hurrah, Christine went back to school for a Doctorate of Nursing Practice degree that was awarded in 2019. Her graduate project was “Using a Smart Phrase to Improve Documentation of Supportive Care Measures in Patients with IPF”. This paper was published in the Journal for Nurse Practitioners and was presented at conferences such as the Pulmonary Fibrosis Foundation and Chest. Christine loves working with ILD patients and have learned so much over the past 9 years working in our clinic. She have been speaking about IPF and progressive ILD for past several years and have so much fun sharing my knowledge with Advanced Care Providers and providers alike.
Lisa Asfahani
PA-C
Lisa Asfahani DHSc, PA-C is a certified and state licensed Physician Assistant practicing in Rheumatology at Southland Arthritis in Temecula, California. Lisa graduated from California State Polytechnic University with a Bachelor’s degree in Biology, her Master’s degree in Physician Assistant Sciences from Loma Linda University in 2011 and her Doctorate degree in Health Sciences from A.T. Still University of Health Sciences in 2022. Lisa is experienced in both Rheumatology as well as in General Medicine and involved in numerous clinical studies in the field of Rheumatology. She is a member of several professional societies including the Association of Rheumatology Professionals (ARP), California Academy of Physician Assistants (CAPA), and RhAPP. Lisa’s goal in patient care is to treat each patient/provider interaction as an opportunity serve, to teach, and to heal. She enjoys traveling and spending time with family whenever she can.
Heather Bachert
NP
Heather D. Bachert, NP, is a board-certified Adult Nurse Practitioner and specializes in interstitial lung disease (ILD) and pulmonary fibrosis (PF) at Henry Ford Hospital in Detroit, Michigan. She earned her advanced practice training at Wayne State University and the University of Saskatchewan and is certified by the American Nurses Credentialing Center. In addition to her clinical role, Heather leads patient support groups for individuals living with ILD and PF, providing education, guidance, and a sense of community. Known for her compassionate and thorough approach, she is highly regarded by patients for her ability to explain complex conditions clearly and provide attentive follow-up care. She is currently accepting new patients and also offers telehealth services.
Shannon Benesh
DNP, NP-C
Shannon Benesh, DNP, RN-BC, AGNP-C, is a Nurse Practitioner specializing in Interstitial Lung Disease at Columbia University Irving Medical Center within the Division of Pulmonary and Critical Care. She earned her BSN from James Madison University and her MSN from Adelphi University, later completing her Doctor of Nursing Practice at Stony Brook University with a project focused on early advance care planning in ILD. Shannon has clinical experience as an RN at leading academic hospitals across various specialties and is certified as a Progressive Care Certified Nurse and Adult-Gerontology Nurse Practitioner. She is an active member of AANP, has contributed to published ILD research, and participates in national advisory boards dedicated to improving ILD care. She lives in Brooklyn with her husband and their dog and enjoys traveling, reading, running, and the occasional cocktail.
Kelley Brant
NP
Kelley Brant, NP, is a nurse practitioner specializing in pulmonology at Intermountain Health in Salt Lake City, Utah. With over 17 years of diverse clinical experience, Kelley Brant is a dedicated healthcare professional with a passion for advancing pulmonary care. A graduate of San Diego State University with a BSN, Kelley began her career as a registered nurse in high-acuity settings, including the emergency room, ICU, and urgent care, where she honed her ability to excel in fast-paced, multidisciplinary environments. Kelley earned her MSN from the University of South Alabama and is double board-certified as a Family Nurse Practitioner and Emergency Nurse Practitioner. For the past 2.5 years, Kelley has served as a nurse practitioner specializing in pulmonary medicine, with a particular focus in interstitial lung disease (ILD). As an ILD program coordinator, Kelley has gained experience in managing complex patient populations and remains actively involved in general pulmonary care, including COPD, asthma, and other respiratory conditions. Kelley also has a strong interest in research, supporting her facility’s participation in several randomized controlled trials to advance evidence-based practice. Beyond clinical work, Kelley is committed to fostering connections within the healthcare community. As a member of AANP, CHEST, and Utah Nurse Practitioners, she emphasizes professional development and collaboration to improve patient outcomes and advance the field of pulmonary care.
Michele Cera
MSN, FNP-BC
April Conlon
NP-C
Kelsey Cramer
MSN, AGACNP-BC, DNP
Kelsey Cramer, MSN, AGACNP-BC, DNP, is a board-certified adult-gerontology acute care nurse practitioner specializing in pulmonary medicine at Froedtert & the Medical College of Wisconsin. She focuses on interstitial lung disease (ILD), pulmonary hypertension (PH), and sarcoidosis. Kelsey earned her MSN and DNP from Rush University and is dedicated to delivering patient-centered care, education, and support for those managing complex lung conditions.
Kristy Delaney
APRN
Kristy Delaney, APRN, is a pulmonary nurse practitioner specializing in interstitial lung disease at The University of Kansas Health System. She has over 21 years of experience in medicine, beginning her career as a bedside RN in the Medical ICU before becoming an APRN. For the past 9 years, she has focused her practice on ILD. In addition to her clinical expertise, Kristy holds a degree in Education and is passionate about empowering patients, caregivers, and fellow healthcare professionals through education and support in the management of ILD.
Rebekah Edwards
DNP, FNP-C
Rebekah Edwards, DNP, FNP-C, is a nurse practitioner specializing in pulmonology at Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center in Phoenix, Arizona. She received her Bachelor of Science in Nursing from Arizona State University and is experienced in pulmonology, cardiology, and thoracic surgery. She also received her Doctorate of Nursing Practice from Arizona State University and has practiced in pulmonology ever since.
Mary Elliott
PA-C, PhD
Kathryn Fenwick
CRNP, DNP
Heather Finlayson
PA-C
Heather Finlayson, MS, PA-C, is a certified Physician Assistant specializing in rheumatology for Summit Rheumatology in Littleton, Colorado. She previously worked at National Jewish Health Rheumatology and started at Colorado Arthritis Associates in Rheumatology in 2012. She has also taught rheumatology courses at Rocky Vista University PA program since 2022. Heather is a member of the Association of Rheumatology Professionals (ARP) (division of American College of Rheumatology-ACR), and the Association of Women in Rheumatology (AWIR). She is currently the AWIR Denver Local Chapter Co-Lead, a Rheumatology Advanced Practice Providers (RhAPP) faculty member and has served on several ACR/ARP committees.
Cori Fratelli
MSN, FNP-C
Cori Fratelli, MSN, FNP-C, is a nurse practitioner specializing in pulmonology at National Jewish Health in Denver, Colorado. She has a unique background in both basic science and clinical research, which has informed her interest in clinical medicine. Her past basic science research includes asthma, airway hyperresponsiveness, cystic fibrosis, and lung cancer. Her past clinical research includes COPD and interstitial lung disease (ILD). Presently, she is interested in how research translates into personalized medicine. Her clinical focus is mainly on ILD, but she also sees general pulmonary medicine patients, as needed.
Kyle George
PA-C
Kyle George, PA-C, is a physician assistant with over 16 years of experience in rheumatology at Saint Luke's Medical Center in Boise, Idaho. He specializes in managing autoimmune diseases such as rheumatoid arthritis and osteoporosis. Kyle collaborates with a multidisciplinary team, providing personalized and comprehensive care to his patients.
Shannon Ghizzoni
PA-C
Shannon Ghizzoni, PA-C, is a board-certified Physician Assistant specializing in rheumatology at the Columbus Arthritis Center in Columbus, Ohio. With a passion for providing comprehensive care to patients with rheumatic conditions, Shannon focuses on patient education, disease management, and improving quality of life. She is dedicated to staying current with the latest advancements in rheumatology and fostering collaborative relationships with patients and healthcare teams to deliver personalized, evidence-based care.
Courtney Gibbons
NP
Courtney Gibbons, MSN, APRN, AGACNP-BC, is a dedicated Pulmonary Nurse Practitioner. With empathy, and compassion, Courtney is committed to delivering evidence-based, patient-centered care to individuals living with complex lung conditions. Her nurse practitioner career has been devoted to pulmonary medicine, to improve quality of life and empower patients. Courtney earned her License at Tyler Junior College then advanced to Registered Nurse in 2016 after completing her Bachelor of Science in Nursing at Indiana State University, and later earned her Master of Science in Nursing with an Adult-Gerontology Acute Care Nurse Practitioner Certification from the University of Texas at Arlington in 2021. Throughout her career, Courtney has been recognized for her dedication to clinical excellence and compassionate care, receiving the Houston Methodist ICARE Award and being named among the Houston Chronicle’s Top 150 Nurses of 2020.
Audrey Gibson
PA-C, MsPAS
Audrey Gibson, MSPAS, PA-C is a board-certified rheumatology physician assistant at the Arthritis Center of North Georgia in Gainesville, Georgia. She holds dual bachelor’s degrees in biology and psychology from Lipscomb University and earned her Master of Science in Physician Assistant Studies from South University in Savannah, Georgia. Audrey is a certified densitometrist with a clinical focus on rheumatoid arthritis, psoriatic arthritis, lupus, spondyloarthropathies, inflammatory myopathies, and osteoporosis. She is an active member of the Society of Physician Assistants in Rheumatology, the Georgia Society of Rheumatology, the American College of Rheumatology, and the American Academy of Physician Assistants. Audrey also serves as a faculty advisor for the Rheumatology Advanced Practice Providers (RhAPP).
Jessica Glennie
CNP
Jessica Glennie, CNP, is a certified nurse practitioner, specializing in pulmonology, who has worked in outpatient pulmonary medicine at the Cleveland Clinic in Cleveland, Ohio for 8 years. She manages patients in the interstitial lung disease program, including care of patients with idiopathic pulmonary fibrosis, autoimmune related interstitial lung disease, hypersensitivity pneumonitis, occupational lung diseases, and drug-induced interstitial lung disease. She is co-director of the Cleveland Clinic’s ILD multidisciplinary conference.
ILD Community Network Educational Events
Bridging APP Specialties: Tackling Interstitial Lung Disease in Systemic Autoimmune Rheumatic Disease
April 09 @ 06:30 pm - 09:30 pm EDT
Bridging APP Specialties: Tackling Interstitial Lung Disease in Systemic Autoimmune Rheumatic Disease
March 19 @ 06:30 pm - 09:00 pm PDT
Bridging APP Specialties: Tackling Interstitial Lung Disease in Systemic Autoimmune Rheumatic Disease
March 26 @ 06:30 pm - 09:00 pm PDT
Bridging APP Specialties: Tackling Interstitial Lung Disease in Systemic Autoimmune Rheumatic Disease
March 31 @ 06:30 pm - 09:00 pm CDT
Bridging APP Specialties: Tackling Interstitial Lung Disease in Systemic Autoimmune Rheumatic Disease
April 16 @ 06:30 pm - 09:00 pm CDT
ILD Digital Learning Center
Podcasts
Podcasts
Podcast: Recognizing PH-ILD Earlier: Missed Signals, Delayed Diagnosis, and How to Close the Gap
February 2026
31:14 m
Pulmonary hypertension associated with interstitial lung disease (PH-ILD) is one of the most impactful—and often underrecognized—complications in patients with established ILD, frequently presenting with symptoms that mimic ILD progression. In this ILD Community Network podcast episode, Amanda Mixon is joined by Corinne Young to break down why PH-ILD is missed, what red flags clinicians should watch for, and when to escalate evaluation beyond “worsening ILD.” The discussion highlights practical screening cues such as disproportionate DLCO decline, stable imaging with worsening dyspnea, enlarged pulmonary arteries on high-resolution CT, and revealing echocardiogram findings including RV/RA enlargement, TAPSE, and tricuspid regurgitation—along with the limitations of echo estimates and the role of right heart catheterization for confirmation. Tune in for real-world strategies to improve earlier recognition, reduce diagnostic delays, and strengthen multidisciplinary collaboration between rheumatology, pulmonology, and primary care to improve outcomes for patients living with ILD and PH-ILD. #InterstitialLungDisease #PulmonaryHypertension #PHILD #Rheumatology #Pulmonology #AdvancedPracticeProviders #MedicalEducation #ILDCommunityNetwork #APAPP #RhAPP
ILD & PH-ILD at the Rheum–Pulm Crossroads
November 2025
22:52 m
Join host Amanda Mixon, President of RhAPP, for a special episode recorded live at the 6th Annual RhAPP Conference. In this conversation, Amanda is joined by Jessica Glennie, CNP, from the Cleveland Clinic, to explore the complex intersection of rheumatology and pulmonology, focusing on Interstitial Lung Disease (ILD) and Pulmonary Hypertension in ILD (PH-ILD). Together, they unpack how early recognition, multidisciplinary collaboration, and evidence-based management can improve outcomes for patients with connective tissue disease–related pulmonary complications. Tune in for expert insights, practical diagnostic tips, and highlights from one of the most engaging sessions of the RhAPP National Conference.
Evolving IPF Care: The Significance of Nerandomilast’s FDA Approval
October 2025
25:20 m
In this special crossover episode, host Amanda Mixon, PA-C, President of RhAPP, sits down with Corinne Young, FNP-C, founder and President of the Association of Pulmonary Advanced Practice Providers (APAPP), to discuss one of the most exciting developments in interstitial lung disease: the FDA approval of nerandomilast for idiopathic pulmonary fibrosis (IPF). This breakthrough marks the first new IPF therapy in more than a decade and introduces a novel PDE4B mechanism of action designed to reduce fibrosis and improve lung function. Together, Amanda and Corrine unpack the clinical data behind nerandomilast, key findings from the FIBRONEER-IPF trial, and how its safety profile—particularly reduced GI side effects—may reshape treatment pathways and patient quality of life. The conversation also highlights the overlap between rheumatology and pulmonology in managing fibrotic lung diseases and the importance of interdisciplinary collaboration as additional indications for progressive pulmonary fibrosis (PPF) are anticipated. #Rheumatology #Pulmonology #InterstitialLungDisease #IPF #Nerandomilast #Fibrosis #AdvancedPracticeProviders #APPs #FDAApproval #ClinicalUpdates
Rheumatology in the Lungs
July 2025
24:47 m
How can Advanced Practice Providers (APPs) in rheumatology and pulmonology collaborate more effectively to manage interstitial lung disease (ILD) and connective tissue diseases (CTDs)? In this engaging episode of the APAPP Broadcast, recorded live at the Second Annual National APAPP Conference in Nashville, experts Jessica Glennie, PA-C (Cleveland Clinic), Amanda Mixon, PA-C (Colorado), and Cori Fratelli, NP (National Jewish Health) explore clinical overlaps between autoimmune rheumatic diseases and lung involvement, such as ILD in rheumatoid arthritis, systemic sclerosis (scleroderma), Sjögren’s syndrome, and myositis. The panel shares clinical pearls on: -How to recognize signs of CTDs in pulmonary patients -The importance of labs and imaging in early diagnosis -What rheumatology APPs should ask about pulmonary symptoms -The power of cross-specialty collaboration -Real-world case insights, including navigating bird-related hypersensitivity pneumonitis
Immunology of the Lung Podcast
July 2025
11:40 m
Tune in from the Annual APAPP National Conference for a dynamic episode of the APAPP Podcast featuring Corinne Young, FNP-C, Amanda Michaud, PA-C, and Brian Bizik, PA-C—three expert APPs leading engaging sessions on lung immunology, rare immune deficiencies, and COPD updates. Amanda breaks down the “Immunology of the Lung 101” and her “Finding the Zebras” series, where she highlights key red flags for primary immune deficiencies, sharing real patient cases and diagnostic tips to help clinicians recognize and manage these commonly missed conditions. Brian shares practical takeaways from the latest GOLD COPD guidelines, including how biomarkers like eosinophil counts can guide personalized inhaled corticosteroid decisions. Whether you're managing patients with asthma, COPD, or unexplained recurrent infections, this episode delivers clinical pearls you can apply in your practice right away. Discover why this APP-led meeting stands out as a must-attend event for pulmonary and immunology providers. Be sure to like, subscribe, and follow us for more expert-driven conversations.
ILD 101, ILD 102, ILD Peds
July 2025
20:57 m
Join Jessica Glennie, APRN, Naomi Miyazawa, PA-C, and Cori Fratelli, FNP, from the 2025 APAPP National Conference as they explore pediatric and adult interstitial lung disease (ILD). This episode covers diagnosis, disease progression, anti-inflammatory and anti-fibrotic therapies, and the importance of multidisciplinary care. Learn about pediatric ILD (CHILD), autoimmune-related ILD, and new treatment guidelines—all through real-world clinical insights.
Advancing ILD & PH-ILD Care
July 2025
21:35 m
Join Jessica Glennie, APRN, and Lori Reed, FNP, from the 2025 APAPP National Conference as they discuss key insights in diagnosing and managing interstitial lung disease (ILD) and pulmonary hypertension (PH). From interpreting PFTs and recognizing red flags to exploring current and emerging therapies like inhaled treprostinil and neuredomast, this episode offers practical strategies for improving patient care. Tune in for expert tips and updates every pulmonary provider should know.
Practical Considerations for Screening for PH in ILD Clinics
July 2025
17:17 m
In this insightful Podcast, expert advanced practice providers, Corinne Young & Jessica Glennie share practical strategies for identifying and screening for pulmonary hypertension (PH) in patients with interstitial lung disease (ILD). They discuss how to recognize subtle red flags—such as declining DLCO, changes in walk test performance, and discrepancies in pulmonary function test results—that may indicate the presence of PH. The conversation also covers when to order echocardiograms, when to refer for right heart catheterization, and how to distinguish ILD progression from the development of PH. With a focus on multidisciplinary collaboration and real-world clinical workflows, this episode offers valuable, actionable guidance for APPs, pulmonologists, and care teams managing ILD populations.
Understanding MAC with Jennifer Faber- Gerling
December 2024
30:30 m
In this episode, Corinne Young interviews Jennifer Faber- Gerling about mycobacterium avian complex (MAC). They discuss the bacterium itself, the rise in cases, screening and diagnosis, treatment and side effects, reinfection versus reactivation, and symptom management. Jennifer emphasized the importance of close surveillance, collaboration with a multidisciplinary team, and individualized care for patients with MAC.
Idiopathic Shortness of Breath Part 1 Using CPET
December 2024
26:37 m
National Jewish Health’s NP, Cori Fratelli, shares with us how she and her colleagues utilize CPET and other testing in patients with unexplained shortness of breath.
Idiopathic Shortness of Breath part 2 Dysfunctional Breathing Clinic
December 2024
29:41 m
Nurse practitioner Cori Fratelli from National Jewish Health discusses breathing pattern disorders, related to unexplained dyspnea. Cori advocates to consider these disorders, discusses treatment methods like breath retraining, inspiratory muscle training, and emphasizes the need for more research and specialized clinics.
Deep Dive Into ILD Therapeutics
December 2024
37:59 m
Check out this podcast recording from the 2024 APAPP Conference in Vegas!
FAQ
FAQ
How can clinicians distinguish PH-ILD from progression of interstitial lung disease alone?
February 2026
08:11 m
In this clinical update, Jessica Glennie, CNP, from the Cleveland Clinic Interstitial Lung Disease Group, explains how to differentiate worsening interstitial lung disease (ILD) or progressive pulmonary fibrosis (PPF) from developing or worsening pulmonary hypertension (PH). Because patients often present with overlapping symptoms such as shortness of breath, fatigue, and decreased exercise tolerance, she outlines a practical diagnostic approach using NT-proBNP, spirometry (FVC), DLCO trends, the FVC/DLCO ratio, six-minute walk testing, high-resolution CT imaging, echocardiogram findings (including RVSP and TAPSE), and when to consider right heart catheterization. This concise review helps clinicians determine whether pulmonary hypertension or ILD progression is driving a patient’s decline and supports more informed clinical decision-making.
What Were The Key Findings From the FIBRONEER-IPF Study?
October 2025
03:51 m
In this FAQ video, Corinne Young, FNP-C, founder and president of the Association of Pulmonary Advanced Practice Providers (APAPP), breaks down the pivotal FIBRONEER-IPF Phase 3 trial evaluating nerandomilast, a novel oral PDE4B inhibitor for patients with idiopathic pulmonary fibrosis (IPF). This randomized, double-blind, placebo-controlled study assessed nerandomilast both as monotherapy and in combination with existing antifibrotic therapies such as pirfenidone and nintedanib. Over 52 weeks, investigators observed that nerandomilast slowed lung function decline (FVC), reduced exacerbations and hospitalizations, and demonstrated a safety profile comparable to placebo, with notably fewer gastrointestinal side effects than traditional antifibrotics. These findings mark an exciting advancement in IPF management, offering clinicians a new therapeutic option that may improve both tolerance and long-term outcomes. #IPF #Nerandomilast #FIBRONEERIPF #Pulmonology #AntifibroticTherapy #PDE4B #InterstitialLungDisease #AdvancedPracticeProviders #APPs #ClinicalTrials #FDAApproval
Med Review
Med Review
Recommended Dosing Strategy For Nerandomilast and Key Adverse Effects To Watch For
December 2025
03:42 m
In this medication review, Corinne Young, Pulmonary Nurse Practitioner and President of the Association of Pulmonary Advanced Practice Providers (APAPP), provides a clear overview of nerandomilast, a newly approved therapy for idiopathic pulmonary fibrosis (IPF). Corinne explains recommended dosing strategies—including 18 mg twice daily as the target dose—along with when to use alternative dosing in combination with pirfenidone or nintedanib, and important considerations for patients taking CYP3A inhibitors. She also reviews the key adverse effects clinicians should monitor, including diarrhea, GI symptoms, mood changes, fatigue, dizziness, headache, and potential allergic reactions. This concise breakdown helps clinicians understand how to dose nerandomilast safely, manage side effects, and optimize treatment for patients with IPF. #IPF #IdiopathicPulmonaryFibrosis #PulmonaryCare #Nerandomilast #IPFTreatment #PulmonaryFibrosis #InterstitialLungDisease #ILD #APPeducation #PulmonaryAPP
Webcast
Webcast
Emerging Therapies in ILD
October 2025
07:37 m
In this presentation, Corinne Young reviews the latest advances in therapies for interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF), highlighting the promising results of nerandomilast, a phosphodiesterase-4B inhibitor with both antifibrotic and immunomodulatory effects. Phase 3 trials (FIBRONEER-IPF and FIBRONEER-ILD) demonstrated that twice-daily nerandomilast slowed lung function decline and improved outcomes across patient populations, including those with autoimmune-related disease. The discussion also covers the drug’s safety profile—showing fewer gastrointestinal side effects compared to existing antifibrotic agents—and emerging treatments such as inhaled treprostinil, which is being studied for pulmonary fibrosis beyond pulmonary hypertension. With multiple new agents and combination therapies on the horizon, these developments represent meaningful progress in the treatment and management of fibrotic lung disease.
Antifibrotic Therapy
October 2025
06:40 m
In this session, Corinne Young reviews the evolution of antifibrotic therapies for interstitial lung disease, beginning with the 2015 U.S. approval of pirfenidone (Esbriet) for idiopathic pulmonary fibrosis (IPF). Pirfenidone works by targeting TGF-β and TNF-α to slow fibroblast proliferation and collagen synthesis, though patients often experience gastrointestinal side effects and fatigue. The discussion also covers nintedanib (Ofev), a tyrosine kinase inhibitor that blocks multiple growth factor pathways (VEGF, FGF, PDGF) and is now approved for both IPF and other progressive fibrotic lung diseases. Clinical trials such as CAPACITY, ASCEND, INPULSIS, and INBUILD demonstrated that these antifibrotics significantly slow the rate of lung function decline and disease progression. The talk concludes by emphasizing careful side-effect management, liver monitoring, and appropriate patient selection to optimize outcomes with these cornerstone antifibrotic therapies.
The Rheum-Pulm Interface: Bridging Specialties in SARD-ILD
October 2025
11:21 m
In this session, Corinne Young and Wendy Simmons highlight the importance of a multidisciplinary approach to managing interstitial lung disease (ILD) in patients with systemic autoimmune and rheumatologic disorders. Collaboration between rheumatology, pulmonology, and radiology teams is key to early recognition, diagnosis, and treatment planning—especially given the high risk of ILD-related morbidity and mortality in conditions like systemic sclerosis, rheumatoid arthritis, lupus, and Sjögren’s syndrome. The discussion reviews ACR screening guidelines, emphasizing the role of high-resolution CT imaging, pulmonary function testing, and oxygen desaturation monitoring. It also covers evidence-based first-line and escalation therapies, including mycophenolate, cyclophosphamide, and rituximab, while underscoring the need for frequent assessment, early intervention, and coordinated care to improve patient outcomes.
Understanding the Landscape of ILD: Burden, Pathophysiology, and Classification
October 2025
20:49 m
In this presentation, pulmonary nurse practitioner Corinne Young and rheumatology physician assistant Wendy Simmons explore the complex relationship between interstitial lung disease (ILD) and connective tissue diseases (CTDs). Together, they provide a multidisciplinary perspective—highlighting how collaboration between pulmonology, rheumatology, and radiology leads to earlier diagnosis, better management, and improved outcomes. The session covers ILD classifications, common causes such as autoimmune disorders, environmental exposures, and drug toxicities, as well as diagnostic tools including high-resolution CT imaging, pulmonary function testing, and serologic assays. The speakers also discuss the importance of recognizing progressive phenotypes, understanding imaging patterns like UIP and NSIP, and tailoring therapy based on disease behavior. This session emphasizes that in ILD, time is lung—early recognition and coordinated care are essential to preserving function and extending quality of life.
IPF & PPF: Natural History, Diagnosis, and Management
October 2025
07:52 m
In this educational session, Corinne Young breaks down the underlying mechanisms, progression, and management of idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILDs). The discussion covers common genetic and environmental risk factors—including family history, smoking, and occupational exposures—and explains how chronic inflammation leads to fibrosis and loss of lung elasticity. Listeners gain a clear understanding of how progressive pulmonary fibrosis is identified through lung function tests (FVC, DLCO) and imaging changes over time. The presentation also addresses treatment strategies, highlighting when corticosteroids may be appropriate, why long-term steroid use is limited, and how newer antifibrotic and immunomodulatory therapies are improving outcomes for patients with fibrotic lung disease.
Rheumatoid Arthritis Associated ILD, End Stage Therapy, and Multidisciplinary Care
October 2025
02:31 m
In this discussion, Corinne Young explores the complexities of managing patients with advanced interstitial lung disease, emphasizing the importance of early referral for lung transplant and cautious evaluation of unproven stem cell therapies. The conversation highlights how patients are sometimes misled into costly, non-evidence-based treatments abroad and underscores that only limited data exist for hematopoietic stem cell use in this setting. The speakers stress the critical role of multidisciplinary collaboration among pulmonology, rheumatology, gastroenterology, and cardiology teams, along with early conversations about palliative care and quality-of-life goals. With new therapies emerging, the focus remains on preserving lung function, aligning treatment with patient priorities, and ensuring compassionate, coordinated care for those facing progressive disease.
What Can Pulmonology APPs Do Once They've Established an ILD Diagnosis to Aid in Potential Rheumatology Workups?
July 2025
01:42 m
Once you've confirmed a diagnosis of interstitial lung disease (ILD), what’s next? In this practical and fast-paced discussion, Amanda Mixon, PA-C, shares actionable steps for evaluating patients for underlying autoimmune or connective tissue diseases. Learn what symptoms to ask about—joint pain, morning stiffness, skin lesions, Raynaud’s, dry eyes or mouth—and how labs and rheumatology collaboration can support early detection and accurate diagnosis. This video offers clinical pearls for APPs working in pulmonology who want to strengthen their diagnostic acumen and build better cross-specialty communication with rheumatology colleagues. Topics covered: – What symptoms may signal underlying rheumatic disease in ILD patients – Key lab tests to guide your differential – When to refer to rheumatology – The value of real-time collaboration across specialties ILD care is better together. Watch now to improve your approach to autoimmune workups in pulmonary patients.
Scleroderma Treatment
July 2025
01:52 m
In this focused discussion, Amanda Mixon, PA-C shares a practical approach to managing patients with systemic sclerosis (Scleroderma), with an emphasis on individualized care based on disease manifestation. From echocardiograms to pulmonary imaging, medication choices to vascular complications, this talk provides key insights into how APPs can tailor care to improve outcomes. Learn how to approach limited vs. diffuse Scleroderma, when to avoid glucocorticoids, and how to manage complications like digital ulcers and pulmonary involvement. Key takeaways include: – When to use echocardiograms, CT scans, and other diagnostics – Medication strategies: Mycophenolate, Selenomab, CCBs, ARBs, and more – Avoiding glucocorticoids in diffuse disease and managing risk of renal crisis – Treating symptomatically: digital ulcers, skin fibrosis, and blood flow support This is a must-watch for APPs in rheumatology, pulmonology, or primary care managing patients with Scleroderma.
Systemic Sclerosis Presentation
July 2025
11:52 m
In this powerful and personal clinical reflection, Amanda Mixon, PA-C, shares her journey treating patients with diffuse systemic sclerosis (Scleroderma), including key lessons learned from working at a major Scleroderma center at Northwestern. From building trust with colleagues to managing life-threatening complications like Scleroderma Renal Crisis, this video offers invaluable insights for APPs and clinicians navigating this complex autoimmune disease. You’ll hear firsthand experiences treating patients with severe skin involvement, pulmonary fibrosis, digital ulcers, GI complications, and early vasculopathy. Learn why RNA polymerase III positivity is a red flag, how to differentiate diffuse from limited SSc, and why early diagnosis and treatment are essential. What you’ll learn: – What distinguishes diffuse Scleroderma from limited forms – Clinical signs to recognize early: Raynaud’s, skin tightening, telangiectasia – The dangers of steroid use and Scleroderma Renal Crisis – Why collaboration and early referral to SSc centers can save lives – Real stories and clinical pearls from treating high-risk patients This is a must-watch for any clinician managing autoimmune diseases—especially those treating interstitial lung disease, GI complications, or vasculitis related to Scleroderma.
Idiopathic Inflammatory Myopathies and Pulmonary Disorders Including ILD
July 2025
04:59 m
Inflammatory myopathies—like dermatomyositis, polymyositis, and inclusion body myositis—can be difficult to diagnose and manage, especially when they overlap with interstitial lung disease (ILD). In this clinical discussion, Amanda Mixon, PA-C, breaks down what to look for, from subtle signs like "mechanic's hands" to more serious red flags like MDA5-positive rapidly progressive ILD. Special attention is given to anti-synthetase syndrome, a condition often associated with ILD, arthritis, and elevated CK levels, and how antibody testing (e.g., Jo-1, SSA, MDA5) can guide diagnosis and urgency of care. You’ll also learn how to approach cancer screenings in patients with dermatomyositis and why a full malignancy workup is essential. What you'll learn: – How to identify anti-synthetase syndrome and inflammatory myopathies – Key clinical signs: weakness, mechanic’s hands, non-erosive arthritis – Understanding the myositis antibody panel and its clinical utility – The connection between dermatomyositis and malignancy risk – When and how to conduct a thorough cancer screening – Treatments including JAK inhibitors, IVIG, and rituximab Perfect for APPs, pulmonologists, and rheumatology teams, this video empowers you to catch early signs, personalize diagnostics, and take action.
Limited Cutaneous Scleroderma Presentation
July 2025
01:48 m
In this quick but focused clinical overview, Amanda Mixon, PA-C, explains how to identify and differentiate limited systemic sclerosis (also known as CREST syndrome) from diffuse scleroderma. Associated with centromere antibodies, limited scleroderma primarily affects the distal extremities and face, and while skin involvement is less severe, patients face distinct long-term risks—especially pulmonary hypertension. This video breaks down the classic CREST acronym (Calcinosis, Raynaud’s, Esophageal dysmotility, Sclerodactyly, and Telangiectasias), along with practical tips for early recognition and long-term management. What you'll learn: – How to recognize clinical features of limited scleroderma – The role of centromere antibodies vs. SCL-70 in diagnosis – Early signs like Raynaud’s and esophageal symptoms – What to monitor for in years 5–10: pulmonary hypertension, vascular disease – Differentiating CREST from diffuse disease This is an essential update for APPs and clinicians managing autoimmune connective tissue disease, especially in patients with progressive symptoms involving the skin, GI tract, and lungs.
Sjogren’s Disease and ILD
July 2025
01:43 m
In this concise and clinically insightful discussion, Amanda Mixon, PA-C, breaks down what to look for when suspecting Sjögren’s syndrome—an autoimmune condition marked by chronic dry eye and dry mouth, fatigue, and systemic manifestations. Often associated with SSA and SSB antibodies, Sjögren’s can overlap with interstitial lung disease (ILD), making it especially important for pulmonary and rheumatology providers to recognize early. Learn how to distinguish classic symptoms from environmental causes, when to consider antibody testing, and which patients may be at higher risk for more severe complications like ILD. What you’ll learn: – Clinical clues for identifying Sjögren’s in practice – Role of SSA and SSB antibodies in diagnosis – Recognizing extra-glandular manifestations: fatigue, arthritis, rashes – When to suspect ILD in Sjögren’s patients – Medication options and early steroid use considerations Whether you’re in primary care, pulmonology, or rheumatology, this video equips you to ask the right questions and understand the systemic risks behind what may appear to be “just dry mouth.”
Industry Resources
Identifying and Monitoring Autoimmune ILD | Insights in ILD
Pulmonary Function Tests (PFTs) Pocket Guide | Insights in ILD
HRCT Pocket Guide | Insights in ILD
History Taking Pocket Guide | Insights in ILD
WANT EXPERT PERSPECTIVES ON INTERSTITIAL LUNG DISEASE?
Imaging Atlas of Interstitial Lung Diseases | Insights in ILD
Rad Rounds UIP to IPF Mobile Application
Rad Rounds - UIP to IPF is an innovative, peer-reviewed resource that provides practicing and future pulmonologists and radiologists with training and references for recognizing and evaluating usual interstitial pneumonia (UIP) and interstitial lung diseases (ILDs) on high resolution computed tomography (HRCT). Through this application the user can access learning materials such as a step-by-step pattern recognition algorithm, utilizing user-provided HRCT scans, an interactive UIP/ILD glossary and image gallery to further assist in the evaluative process, several “test your knowledge” quizzes, and a series of short informational videos, covering subjects such as: Basic HRCT Technique, Imaging Positions, and Recognizing Features of ILD on HRCT. This app is ideal for: radiologists that would like to use the interactive algorithm to help assess their HRCT scans, pulmonologists that want to evaluate their own cases or learn more about HRCT in the diagnosis of ILD, and medical students and residents that want to learn about HRCT and ILD. Download now and find out: Is It UIP? Available on the App Store: https://apps.apple.com/us/app/rad-rounds-uip-to-ipf/id1327938328 Available on Google Play: https://play.google.com/store/apps/details?id=com.boehringer.radiologyrounds&hl=en_US
News
News
Advancing practitioner knowledge in interstitial lung disease: a review of free, online resources
March 2026
CONCLUSIONS: This review provides a catalog of free online ILD educational resources that can supplement ILD education for non-ILD expert practitioners. These resources address identified knowledge gaps and can be utilized for self-directed learning or integration into formal training curricula.
Polypropylene flock exposure and respiratory outcomes among manufacturing workers
March 2026
Occupational exposure to polypropylene flock may increase the risk of respiratory symptoms and disease. A cross-sectional study evaluated respiratory effects of polypropylene flock among workers at a large manufacturing facility. Participants completed a questionnaire and spirometry testing; those with abnormal findings received a physical examination. Exposure was based on work history in polypropylene production rooms. Fifty-five workers (39 exposed; 16 unexposed) participated. Exposed workers...
Genetic and pharmacologic inhibition of calcineurin reduces biofilm formation by the pathogenic fungus Trichosporon asahii in an in vivo silkworm infection model
March 2026
Trichosporon asahii is a dimorphic pathogenic fungus that causes catheter-related bloodstream infection in immunocompromised patients with neutropenia. Biofilm formation by T. asahii on the surfaces of medical devices such as catheters is influenced by various host environmental factors. Calcineurin, a protein phosphatase composed of the catalytic subunit Cna1 and the regulatory subunit Cnb1, regulates multiple stress responses and virulence of T. asahii. The role of calcineurin in biofilm...
Clinical features and outcomes of childhood interstitial lung disease: a tertiary center experience
March 2026
CONCLUSION: This study presents one of the largest single-center pediatric chILD cohorts reported from Türkiye. It highlights the prognostic relevance of baseline hypoxia and underscores the importance of comprehensive radiological and genetic assessment in the management of chILD.
Quantitative comparative analysis of different CT modalities in systemic sclerosis-associated interstitial lung disease: correlations with lung function, serological biomarkers, and disease stratification
March 2026
CONCLUSIONS: HRCT, MonoE 70 keV CT, and VNC CT exhibit distinct and complementary advantages in the assessment of SSc-ILD. Quantitative CT parameters reflect disease severity, with MonoE 70 keV CT demonstrating strengths in lung volume analysis and VNC CT showing potential value in serological disease activity assessment, thereby supporting diagnosis and individualized disease management.
Prognostic factors in combined pulmonary fibrosis and emphysema: a systematic review and meta-analysis
March 2026
CONCLUSIONS: Age, smoking history, DLCO, DLCO%pred, lung cancer, an annual increase in CPI(≥5points), and UIP pattern on HRCT may be prognostic factors for mortality in patients with CPFE. Lung cancer may be a prognostic factor for AE in CPFE patients. However, due to the limited number and quality of the included studies, these conclusions need to be validated by further research.
Relationship between immune-related adverse events and treatment outcome of immune checkpoint inhibitors for advanced non-small cell lung cancer: a retrospective cohort study
March 2026
CONCLUSIONS: The occurrence of irAEs is associated with improved response and survival, whereas ILD may not reflect antitumor immunity. These findings emphasize the need for detailed toxicity profiling when interpreting irAEs as potential biomarkers in immunotherapy.
Crizotinib attenuates bleomycin-induced pulmonary fibrosis via regulating fibroblast activation
March 2026
CONCLUSIONS: Through suppressing fibroblast proliferation and activation, crizotinib could alleviate pulmonary fibrosis in BLM induced mice. Crizotinib could inhibit the PI3K/AKT/mTOR, STAT3 and ERK signaling pathways. Crizotinib might be an emerging medication choice for patients with IPF.
Global and Chinese trends in disease burden of interstitial lung disease and pulmonary sarcoidosis from 1990 to 2021 with projections to 2040: a COVID-19 impact analysis based on the Global Burden of Disease Study 2021
March 2026
CONCLUSIONS: Due to the impact of COVID-19, the global and Chinese burden of ILD and sarcoidosis showed a decline during 2019-2021, interrupting its previous upward trend. The disease burden was particularly severe among economically disadvantaged regions, elderly populations and males. While projections indicate a potential stabilization or decline in ASRs through 2040, these trends must be interpreted with caution due to potential confounding effects of pandemic-related diagnostic disruptions....
A Case Series of Lymphangioleiomyomatosis, a Rare Cystic Lung Disease
March 2026
Lymphangioleiomyomatosis (LAM) is a rare interstitial lung disease that predominantly affects women of childbearing age. In this case series, we presented five cases diagnosed with LAM in our clinic in the last 2 years. All cases were female, and their ages ranged from 40 to 54 years. The primary symptoms of LAM seen in the cases were exertional dyspnea and cough. Radiological examination revealed multiple bilateral thin-walled air cysts on high-resolution computed tomography (HRCT) in all...
Pleuroparenchymal Fibroelastosis Complicated by Pulmonary Alveolar Proteinosis After Peripheral Blood Stem Cell Transplantation
March 2026
A 52-year-old man with a history of Philadelphia chromosome-positive acute lymphoblastic leukaemia underwent peripheral blood stem cell transplantation (PBSCT) 10 years earlier. Five years after transplantation, he developed a persistent dry cough and exertional dyspnea. High-resolution CT revealed upper lobe-predominant subpleural fibrosis compatible with pleuroparenchymal fibroelastosis (PPFE) and lower lobe reticulation with ground-glass opacities. Video-assisted thoracoscopic lung biopsy...
A case report of idiopathic pulmonary fibrosis concurrent with EGFR 19 deletion lung adenocarcinoma
March 2026
CONCLUSIONS: This report aims to enhance clinicians' understanding of pulmonary fibrosis complicated by lung cancer. Tumor molecular testing is also important in patients with NSCLC concurrent with IPF. Furthermore, it provides preliminary clinical evidence suggesting that, with careful monitoring and concomitant anti-fibrotic therapy, EGFR-TKIs like Icotinib may represent a viable treatment option for patients co-existing with IPF and EGFR-mutated NSCLC.
Characterising Patient Pathways Prior to the Diagnosis of Interstitial Lung Disease
March 2026
CONCLUSION: Gradual onset of non-specific symptoms over 10 years, coupled with referrals to other specialities and misdiagnoses, delays ILD diagnosis. Improving awareness of ILD among primary care practitioners may shorten the time to diagnosis and expedite access to treatments.
Antineutrophil cytoplasmic antibody-associated vasculitis with initial gastrointestinal symptoms: case series and literature review
March 2026
CONCLUSION: Gastrointestinal symptoms in AAV are rare, and misdiagnosis remains a concern. Early detection requires assessing gastrointestinal, pulmonary, and renal involvement.
Lung involvement in rheumatoid arthritis
March 2026
Pulmonary involvement in rheumatoid arthritis is common and affects nearly half of patients. It can involve all pulmonary structures. However, interstitial lung disease is the most frequent manifestation and the most significant in terms of prognosis. Diagnosis relies on chest computed tomography, and prognosis depends especially on disease extent and radiological pattern. Management requires multidisciplinary discussion and is based on an individualized strategy combining control of articular...
How the Fibrotic Lung Microenvironment Regulates Stem Cell Behavior: Immune Cues, Extracellular Matrix Remodeling, and Therapeutic Implications
March 2026
Pulmonary fibrosis (PF) is a chronic and progressive interstitial lung disease characterized by excessive extracellular matrix (ECM) deposition and remodeling of lung structures. Currently, no effective clinical treatments exist to reverse or halt the progression of PF. Consequently, there is an urgent need to identify novel therapeutic strategies for this complex disease. Stem cells, renowned for their self-renewal and multipotent differentiation capabilities, have garnered considerable...
Prevention and management of gastrointestinal side effects in patients with systemic sclerosis-interstitial lung disease receiving anti-fibrotic therapy: a modified Delphi consensus study
March 2026
CONCLUSIONS: This study provided a detailed list of expert-based recommendations to guide everyday clinical practice of SSc-ILD, though prospective validation is needed to confirm their effectiveness in preventing and managing GI side effects.
Metformin attenuates fructose-induced pulmonary fibrosis, possibly through the involvement of the TRPC6 channel
March 2026
Pulmonary fibrosis is a chronic, progressive, fatal lung disease characterized by abnormal lung tissue repair and intense collagen accumulation in the lungs. Despite intensive efforts, no specific treatment has been found. The aim of this study was to investigate the effects of a high-fructose diet on lung tissue, whether the use of metformin corrects the damage caused by high fructose, and the possible relationship with transient receptor potential (TRP) channels. Lung damage was induced by...
Fibroblast-activation protein inhibitors based positron emission tomography (PET) for assessing lung disease: A systematic review with meta-analysis
March 2026
CONCLUSION: Our results show that FAPI PET/CT has an excellent diagnostic performance for lung tumours and non-tumour lesions.Points for clinical research: Currently CT is unable to accurately determine the activity of lung diseases such as IPF and hence may lead to delays in the diagnosis and treatment of some lung diseases. We aimed to find evidence-based medical evidence suitable for FAPI PET in lung diseases, especially non-oncological diseases, by performing a meta-analysis of FAPI PET in...
Safety and Efficacy of Nerandomilast in Patients With Pulmonary Fibrosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
March 2026
CONCLUSION: Nerandomilast appears to slow lung function decline in pulmonary fibrosis without added safety risks. Although a lower pooled risk of mortality was observed, individual trials were not powered for mortality outcomes, and event rates were low; therefore, this finding should be interpreted cautiously. Given the heterogeneity of pulmonary fibrosis phenotypes and trial designs, further large-scale RCTs should explore standardized outcomes, subgroup effects, and combination strategies...
