Platypnea-orthodeoxia syndrome - a rare presentation and diagnostic challenge
July 2026
News
Platypnea-orthodeoxia syndrome (POS) is a rare condition which presents with positional dyspnoea and deoxygenation on an orthopneic position which resolves when supine. We present a rare presentation of POS in a 75-year-old man, who initially presented with mixed symptomology including dyspnoea on exertion and syncope. He was found to have intermittent symptomatic hypoxia and initial investigations ruled out infection, pulmonary embolism and interstitial lung disease. Pulse oximetry confirmed...